Evidence Suggesting the Beneficial use of Magnesium in Cerebral Ischaemia in an Experimental Model of Cardiac Arrest
نویسندگان
چکیده
Introduction: Brain damage is one of the major causes of morbidity and mortality in cardiac arrest victims. The aim of the present study was to determine whether administration of magnesium during cardiopulmonary resuscitation would improve post-resuscitation cerebral injury, as indicated by cerebral ischaemia markers and neurological alertness
منابع مشابه
Initial documented rhythm as a predictor of survivalto-discharge rate after in-hospital cardiac arrest in a tertiary care referral institute, South India: an observational study
Objective: Survival-to-discharge rates following in-hospital cardiac arrest (IHCA) patients remain significantly low. The use of initial documented cardiac rhythm as predictor of Survival-to-discharge is still unclear. This study aimed to assess whether the initial documented rhythm can be used as a predictor of survival-to-discharge following IHCA in an emergency department of the tertiary car...
متن کاملA Study of Cerebral Performance Categories Based on Initial Rhythm and Resuscitation Time Following In-Hospital Cardiac Arrest in a State Hospital in Turkey
Background: The cerebral performance category (CPC) score is widely used in research and quality assurance to assess neurologic outcome following cardiac arrest. However, little is known about the results of the CPC in Turkey. Objective: This study aimed to determine whether the CPC is associated with the initial rhythm and resuscitation time following re...
متن کاملEffects of mild hypothermia on expression of NF-E2-related factor 2 and heme-oxygenase-1 in cerebral cortex and hippocampus after cardiopulmonary resuscitation in rats
Objective(s): The aim of this study was to investigate the effects of mild hypothermia on expression of NF-E2-related factor 2 (Nrf2) and heme-oxygenase-1 (HO-1) of rat cerebral cortex and hippocampus after cardiopulmonary resuscitation and further investigate the possible mechanism of action. Material and Methods:To copy an asphyxia heart arrest model, Sprague Dawley rats were randomly divided...
متن کاملMagnesium in subarachnoid haemorrhage: proven beneficial?
Subarachnoid haemorrhage (SAH) caused by a ruptured aneurysm accounts for only 5% of strokes, but occurs at a fairly young age and carries a worse prognosis. Delayed cerebral ischaemia (DCI) is an important cause of death and dependence after aneurysmal subarachnoid haemorrhage. The current mainstay of preventing DCI is nimodipine and maintenance of normovolemia, but even with this strategy DCI...
متن کاملMagnesium in subarachnoid haemorrhage: proven beneficial?
Subarachnoid haemorrhage (SAH) caused by a ruptured aneurysm accounts for only 5% of strokes, but occurs at a fairly young age and carries a worse prognosis. Delayed cerebral ischaemia (DCI) is an important cause of death and dependence after aneurysmal subarachnoid haemorrhage. The current mainstay of preventing DCI is nimodipine and maintenance of normovolemia, but even with this strategy DCI...
متن کامل